Nutraceuticals

Nutraceutical products are frequently manufactured in a process similar in nature to a pharmaceutical process, with a very wide range of product formats, from powder through to tablet, for a wide range of product types, from botanicals, through to minerals, vitamins and nutritional supplements, and they are subject to many of the controls applied to the pharmaceutical industry.

For products in tablet format, the efficiency of the tableting process is dependent on the end-point moisture and granulation achieved in the exipient in the fluid-bed drier prior to the tablet press. Incorrect moisture at this stage can result in poor tablet formation and even total batch loss, since many formulations cannot be re-worked once released from the drier. Overdrying, however, may result in reduction or destruction of the efficacy of the active ingredients.

In powdered products generally, the moisture content greatly influences product quality characteristics such as shelf-life longevity, and mechanical characteristics, in terms of packing density.

Real-time on-line or rapid at-line moisture measurements are indespensible in acheiving and maintaining product quality and consistency. TheCM710e On-Line Moisture Gauge makes continuous non-contacting measurements through the fluid bed dryer sight glass, while the InfraLab At-Line Moisture Analyzer can be used to quickly and accurately measure samples thieved from the process, complementing compendial methods written into the Pharmacopeia.

NDC, Moisture measurement in nutraceutical powders, end-point moisture determination

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